Penile Cancer

Fluorescence Diagnosis of Penile Carcinoma - a New Technique to Assist and Control Nd:YAG-Laser Therapy

Author(s): Peter Schneedea, Dominic Frimbergera, Dirk Zaaka and Alfons Hofstetter

The macroscopic lesions of penile cancer are often accompanied by invisible dysplasia, premalignant penile intraepithelial neoplasia (PIN), ill-defined tumor edges or carcinoma in situ (CIS). Since squamous cell carcinomas are not very sensitive to radiation or chemotherapy, the gold standard for the disease is partial or total penectomy. In this study, fluorescence diagnosis is used for the first time in assisting the urologist in the detection of neoplastic and preneoplastic lesions in the rare diagnosis of penile cancer.